Multimodal Deep Learning for Early Detection of Depression and Anxiety through Explainable AI

Mental illness, particularly depression and anxiety, is a leading cause of global disease burden. Underdiagnosis is common due to misperceptions and negative stigma around mental health, limited resources, and self-reporting bias. Newer multimodal deep learning (MDL) frameworks have demonstrated the ability to distill behavioral, linguistic, and physiological signals pertaining to mental health from a number of data streams. However, uptake in clinical practice has been limited partly due to lack of transparency in how the models reach their conclusions. This study proposes a multimodal deep learning framework for the automatic early detection of anxiety and depression from text, audio and video signals with a special focus on Explainable AI(XAI). Basing the research on the benchmark datasets DAIC-WOZ, E-DAIC, and eRisk, the model outperformed unimodal baselines, and delivered clinically meaningful results that were interpretable. The research shows that leveraging explanatory artificial intelligence with MDL frameworks can create a more reliable and transparent AI-based screening tool for mental health problems.

Institutions

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-09-30
DOI
https://doi.org/10.5281/zenodo.17311572
Primary Topic
Ecology and Vegetation Dynamics Studies
Type
article
Field-Weighted Citation Impact
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article

Multimodal Deep Learning for Early Detection of Depression and Anxiety through Explainable AI

Zenodo (CERN European Organization for Nuclear Research)
Ecology and Vegetation Dynamics Studies
article

Multimodal Deep Learning for Early Detection of Depression and Anxiety through Explainable AI

article en

Abstract

Mental illness, particularly depression and anxiety, is a leading cause of global disease burden. Underdiagnosis is common due to misperceptions and negative stigma around mental health, limited resources, and self-reporting bias. Newer multimodal deep learning (MDL) frameworks have demonstrated the ability to distill behavioral, linguistic, and physiological signals pertaining to mental health from a number of data streams. However, uptake in clinical practice has been limited partly due to lack of transparency in how the models reach their conclusions. This study proposes a multimodal deep learning framework for the automatic early detection of anxiety and depression from text, audio and video signals with a special focus on Explainable AI(XAI). Basing the research on the benchmark datasets DAIC-WOZ, E-DAIC, and eRisk, the model outperformed unimodal baselines, and delivered clinically meaningful results that were interpretable. The research shows that leveraging explanatory artificial intelligence with MDL frameworks can create a more reliable and transparent AI-based screening tool for mental health problems.

Zenodo (CERN European Organization for Nuclear Research)
University of Bahrain (BH)
Quality Education
Openalex Percentile: Top 39%
Ecology and Vegetation Dynamics Studies
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Multimodal Deep Learning for Early Detection of Depression and Anxiety through Explainable AI · Zenodo (CERN European Organization for Nuclear Research) (2025) | TGRS Research Map | TGRS