ACUTE RHEUMATOID FEVER

Acute Rheumatic Fever (ARF) is an autoimmune inflammatory disorder following Streptococcus pyogenes infection, affecting the heart, joints, skin, and nervous system. Management focuses on symptom relief and prevention of recurrence. NSAIDs control fever and arthritis, glucocorticoids treat severe carditis, and antibiotics, particularly benzathine penicillin, eradicate infection and provide long-term prophylaxis. Understanding the mechanisms, indications, dosing, and side effects of these drugs is crucial for effective care. Early diagnosis and timely treatment significantly reduce morbidity and prevent progression to rheumatic heart disease.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-10-09
DOI
https://doi.org/10.5281/zenodo.17302657
Primary Topic
Child Development and Digital Technology
Type
article
Field-Weighted Citation Impact
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article

ACUTE RHEUMATOID FEVER

Zenodo (CERN European Organization for Nuclear Research)
Child Development and Digital Technology
article

ACUTE RHEUMATOID FEVER

article en

Abstract

Acute Rheumatic Fever (ARF) is an autoimmune inflammatory disorder following Streptococcus pyogenes infection, affecting the heart, joints, skin, and nervous system. Management focuses on symptom relief and prevention of recurrence. NSAIDs control fever and arthritis, glucocorticoids treat severe carditis, and antibiotics, particularly benzathine penicillin, eradicate infection and provide long-term prophylaxis. Understanding the mechanisms, indications, dosing, and side effects of these drugs is crucial for effective care. Early diagnosis and timely treatment significantly reduce morbidity and prevent progression to rheumatic heart disease.

Zenodo (CERN European Organization for Nuclear Research)
Osh State University (KG)
Good health and well-being
Openalex Percentile: Top 35%
Child Development and Digital Technology
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ACUTE RHEUMATOID FEVER · Zenodo (CERN European Organization for Nuclear Research) (2025) | TGRS Research Map | TGRS