Anaplastic Large Cell Lymphoma, ALK-Negative: A Rare Case with Histopathological and Immunohistochemical Features

We report a case of anaplastic large cell lymphoma (ALCL), ALK-negative, diagnosed in a 27-year-old patient presenting with diffuse lymphadenopathy and constitutional symptoms. Histopathological examination revealed sheets of large pleomorphic lymphoid cells, and immunohistochemistry demonstrated CD30 positivity with ALK negativity. This case highlights the diagnostic and therapeutic challenges associated with this rare subtype of T-cell lymphoma and contributes to the growing body of literature on ALCL ALK-negative.

Institutions

Publication Details

Journal
Brazilian Journal of Case Reports
Published
2025-10-09
DOI
https://doi.org/10.52600/2763-583x.bjcr.2026.6.1.bjcr124
Primary Topic
Wastewater Treatment and Nitrogen Removal
Type
article
Field-Weighted Citation Impact
0.00

Funders

Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Anaplastic Large Cell Lymphoma, ALK-Negative: A Rare Case with Histopathological and Immunohistochemical Features

Brazilian Journal of Case Reports
Wastewater Treatment and Nitrogen Removal
article

Anaplastic Large Cell Lymphoma, ALK-Negative: A Rare Case with Histopathological and Immunohistochemical Features

article en

Abstract

We report a case of anaplastic large cell lymphoma (ALCL), ALK-negative, diagnosed in a 27-year-old patient presenting with diffuse lymphadenopathy and constitutional symptoms. Histopathological examination revealed sheets of large pleomorphic lymphoid cells, and immunohistochemistry demonstrated CD30 positivity with ALK negativity. This case highlights the diagnostic and therapeutic challenges associated with this rare subtype of T-cell lymphoma and contributes to the growing body of literature on ALCL ALK-negative.

Brazilian Journal of Case ReportsVol. 6(1)
Universidade de São Paulo (BR), Biomega (Norway) (NO)
Fundação de Amparo à Pesquisa do Estado de São Paulo, Conselho Nacional de Desenvolvimento Científico e Tecnológico
Peace, Justice and strong institutions
Openalex Percentile: Top 58%
Wastewater Treatment and Nitrogen Removal
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.