Nano Herbal Drug Delivery System: Bridging Ayurveda and Nanotechnology

Ayurveda, the ancient Indian system of medicine, emphasizes holistic health through plant-derived natural substances known for their therapeutic potential and minimal side effects. Despite their benefits, conventional herbal medicines face challenges such as poor solubility, low bioavailability, instability, and limited target specificity, reducing clinical efficacy. This review highlights how nanotechnology can address these limitations by integrating with Ayurveda to develop Nano Herbal Drug Delivery Systems (NHDDS). Nanocarriers, including liposomes, niosomes, solid lipid nanoparticles, nanoemulsions, and microspheres, enhance solubility, stability, controlled release, and targeted delivery of bioactive phytochemicals such as curcumin, ashwagandha, tulsi, and neem. Recent advances, including artificial intelligence-assisted formulation design and green synthesis methods, further improve therapeutic outcomes and promote sustainability. The convergence of ancient Ayurvedic knowledge with modern nanoscience offers a promising platform for developing safer, more effective, and globally acceptable herbal therapies, bridging traditional wisdom with contemporary pharmaceutical innovation.