Polypoid Ganglioneuroma in a Patient with Colonic Polyposis: A Case Report

Ganglioneuromas are benign tumors of the autonomic nervous system. They are rarely found in the colonic mucosa, where symptoms tend to be non-specific. Some patients may present with abdominal pain, changes in bowel habits, hematochezia, ileus, or obstruction. There are few reports in the literature of ganglioneuromas coexisting with colonic polyposis or even adenocarcinoma. We report a case of a 37-year-old man with polypoid ganglioneuroma, colonic polyposis, and a family history of colon cancer, who had a favorable outcome after two years of follow-up. Ganglioneuroma is a neuroectodermal tumor that is rarely observed in the colorectal mucosa. In the case of polypoid ganglioneuroma, as seen in our patient, no syndromic associations were identified. The patient was successfully treated with endoscopic polypectomy, resulting in a favorable clinical outcome.