Simultaneous conjunctival intraepithelial neoplasia and primary pterygium – management using topical 0.02% mitomycin C

The aim of this study was to report a rare case of conjunctival intraepithelial neoplasia (CIN) in conjunction with primary pterygium managed with topical mitomycin C. A 27-year-old man presented with a pterygium and a whitish mass adjacent to it in his right eye and only a pterygium in the left eye. On examination, the lesion showed characteristic feeder vessels adjacent to it. Impression cytological examination did not show any features of dysplasia. The patient was started on topical 0.02% mitomycin C eye drops 4 times a day,1 week on and 3 weeks off. After 1 month of follow-up, there was a marked reduction in the size and vascularity of the lesion. Ocular surface squamous neoplasia and pterygia share risk factors and co-exist in only a minority of cases. Because CIN can occur adjacent to pterygial tissues, long-term follow-up is necessary in patients with pterygia.