Management of Diabetic Peripheral Neuropathy: A Narrative Review

Diabetic neuropathy (DN) is a frequent complication of diabetes mellitus (DM). Diabetic neuropathies are a heterogeneous group of disorders with diverse clinical manifestations This review discusses the risk factors for DN, the main characteristics of the clinical forms of DN, the screening methods and the current therapeutic options. The most important treatment of DN remains good glucose control, generally defined as HbA1c ≤7%. Symptomatic treatment improves life quality in diabetic patients. Pharmacological agents have been validated in several studies since they act on specific pathways such as increased oxidative stress and the excessive production of advanced glycosylation products.