Coupling Generative Modeling and an Autoencoder with the Causal Bridge

We consider inferring the causal effect of a treatment (intervention) on an outcome of interest in situations where there is potentially an unobserved confounder influencing both the treatment and the outcome. This is achievable by assuming access to two separate sets of control (proxy) measurements associated with treatment and outcomes, which are used to estimate treatment effects through a function termed the em causal bridge (CB). We present a new theoretical perspective, associated assumptions for when estimating treatment effects with the CB is feasible, and a bound on the average error of the treatment effect when the CB assumptions are violated. From this new perspective, we then demonstrate how coupling the CB with an autoencoder architecture allows for the sharing of statistical strength between observed quantities (proxies, treatment, and outcomes), thus improving the quality of the CB estimates. Experiments on synthetic and real-world data demonstrate the effectiveness of the proposed approach in relation to the state-of-the-art methodology for proxy measurements.

Publication Details

Journal
ArXiv.org
Published
2025-09-29
Primary Topic
Microbial Community Ecology and Physiology
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article

Coupling Generative Modeling and an Autoencoder with the Causal Bridge

ArXiv.org
Microbial Community Ecology and Physiology
article

Coupling Generative Modeling and an Autoencoder with the Causal Bridge

article en

Abstract

We consider inferring the causal effect of a treatment (intervention) on an outcome of interest in situations where there is potentially an unobserved confounder influencing both the treatment and the outcome. This is achievable by assuming access to two separate sets of control (proxy) measurements associated with treatment and outcomes, which are used to estimate treatment effects through a function termed the em causal bridge (CB). We present a new theoretical perspective, associated assumptions for when estimating treatment effects with the CB is feasible, and a bound on the average error of the treatment effect when the CB assumptions are violated. From this new perspective, we then demonstrate how coupling the CB with an autoencoder architecture allows for the sharing of statistical strength between observed quantities (proxies, treatment, and outcomes), thus improving the quality of the CB estimates. Experiments on synthetic and real-world data demonstrate the effectiveness of the proposed approach in relation to the state-of-the-art methodology for proxy measurements.

ArXiv.org
Openalex Percentile: Top 40%
Microbial Community Ecology and Physiology
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