Precise Prognosis of Hypercholesterolemia and Acute Kidney Diseases by Photonic Crystal Biosensor

In this research, a 2-D photonic crystal based hexagonal shaped system is presented. The designed device is consisted of 35*42 silicon rods (placed in air). Main functionality processes of the proposed biosensor were studied by considering photonic bandgap (PBG) and field distribution spectra. PBG and field diagrams could be obtained by using plane wave expansion (PWE) and finite-difference-time-domain (FDTD) numerical techniques. The designed system could be used for prognosis of cholesterol and creatinine levels in blood (these biological elements are introduced through their refractive indices). At defined wavelengths, incident signal could be transferred along the system and would reach outputs 1 or 2. Output1 could be applied for prognosis of cholesterol concentrations with quality factor ( Q ): ( 55.2 – 66.4 ), sensitivity ( S ): 1204.7nm/RIU , detection limit ( DL ): ( 0.0021–0.0031 ) RIU and figure of merit ( FOM ): ( 48.18–54.6 ) RIU -1 . Output2 would be used for detection of creatinine with ( Q ): ( 175.7–195.5 ), ( S ): 1957.3nm/RIU , ( DL ): ( 4.8e-4 –5.2e-4 ) RIU and ( FOM ): ( 184.8–205.9 ) RIU -1 . Based on the results, proposed device (biosensor) would aid physicians in diagnosis of various serious diseases.