Influence of helicobacteriosis on the development of pancreatic cancer

Helicobacter pylori is considered one of the most widespread bacterial agents affecting the human body. The main known diseases associated with the presence of this pathogen include esophagitis and gastroesophageal reflux disease (GERD), peptic ulcer disease, and gastric cancer. The aim of this work was to investigate the influence of helicobacteriosis on the development of pancreatic cancer. It is known that Helicobacter pylori infection significantly influences the overall cancer morbidity, and it is important to expound on the role of this bacterium in the development of pancreatic cancer in particular. The aim of the work was to investigate the influence of helicobacteriosis on the development of pancreatic cancer. The study was based on the analysis of literature sources from various scientific databases, such as PubMed, Scopus, and Google Scholar, as well as statistical data from official sources, including the World Health Organization (WHO) and the International Agency for Research on Cancer (IARC). The literature review reveals that chronic Helicobacter pylori infection can be a risk factor for pancreatic cancer due to its impact on the systemic inflammatory response, changes in the gastrointestinal microbiota, and the influence on metabolic processes. The study also considers the role of Helicobacter pylori in the development of insulin resistance and metabolic disorders, which may also be linked to the development of pancreatic cancer. The analysis of the current studies has shown that the eradication of Helicobacter pylori can contribute to the reduction of the overall cancer risk, but its direct influence on pancreatic cancer requires further investigation. The paper emphasizes the necessity of comprehensive screening and prevention strategies for Helicobacter pylori infection, especially in high-risk groups, and highlights the importance of early diagnosis and treatment to reduce the morbidity and mortality associated with pancreatic cancer.