HISTOLOGICAL MECHANISMS OF NERVE REGENERATION: NEUROSURGICAL INSIGHTS

The repair of injured nerve tissue represents one of the most complex areas in neurosurgical research. Neural cells demonstrate only partial regenerative ability, which makes both experimental and clinical studies crucial. This article examines the histological processes that underlie nerve repair, focusing on axonal regrowth, Schwann cell proliferation, myelin reconstruction, and the role of trophic molecules. Current neurosurgical practices, including microsurgical suturing, nerve grafts, artificial conduits, and stem cell applications, are analyzed through the lens of histological evidence. The findings suggest that a deeper understanding of microscopic regenerative pathways can significantly improve surgical outcomes and expand opportunities for regenerative neurosurgery.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-10-02
DOI
https://doi.org/10.5281/zenodo.17247766
Primary Topic
Solid-state spectroscopy and crystallography
Type
article
Field-Weighted Citation Impact
0.00
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article

HISTOLOGICAL MECHANISMS OF NERVE REGENERATION: NEUROSURGICAL INSIGHTS

Zenodo (CERN European Organization for Nuclear Research)
Solid-state spectroscopy and crystallography
article

HISTOLOGICAL MECHANISMS OF NERVE REGENERATION: NEUROSURGICAL INSIGHTS

article en

Abstract

The repair of injured nerve tissue represents one of the most complex areas in neurosurgical research. Neural cells demonstrate only partial regenerative ability, which makes both experimental and clinical studies crucial. This article examines the histological processes that underlie nerve repair, focusing on axonal regrowth, Schwann cell proliferation, myelin reconstruction, and the role of trophic molecules. Current neurosurgical practices, including microsurgical suturing, nerve grafts, artificial conduits, and stem cell applications, are analyzed through the lens of histological evidence. The findings suggest that a deeper understanding of microscopic regenerative pathways can significantly improve surgical outcomes and expand opportunities for regenerative neurosurgery.

Zenodo (CERN European Organization for Nuclear Research)
Openalex Percentile: Top 58%
Solid-state spectroscopy and crystallography
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