A Multiwell Liquid-Based Assay for Screening <i>C. elegans</i> Knockdowns

Source: Anderson, Q. L. et al. A High-throughput, High-content, Liquid-based C. elegans Pathosystem. J. Vis. Exp. (2018)This video demonstrates a high-throughput screening method using Caenorhabditis elegans to study gene knockdowns during host-pathogen interactions. It outlines the procedure for preparing knockdown worms and transferring them to assay plates to evaluate the effects of pathogen-induced worm killing.

Publication Details

Journal
Journal of Visualized Experiments
Published
2025-09-26
DOI
https://doi.org/10.3791/24085
Primary Topic
Genomics and Phylogenetic Studies
Type
article
Field-Weighted Citation Impact
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article

A Multiwell Liquid-Based Assay for Screening C. elegans Knockdowns

Journal of Visualized Experiments
Genomics and Phylogenetic Studies
article

A Multiwell Liquid-Based Assay for Screening C. elegans Knockdowns

article en

Abstract

Source: Anderson, Q. L. et al. A High-throughput, High-content, Liquid-based C. elegans Pathosystem. J. Vis. Exp. (2018)This video demonstrates a high-throughput screening method using Caenorhabditis elegans to study gene knockdowns during host-pathogen interactions. It outlines the procedure for preparing knockdown worms and transferring them to assay plates to evaluate the effects of pathogen-induced worm killing.

Journal of Visualized Experiments
Openalex Percentile: Top 47%
Genomics and Phylogenetic Studies
DOISourceOpenAlex
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A Multiwell Liquid-Based Assay for Screening <i>C. elegans</i> Knockdowns · Journal of Visualized Experiments (2025) | TGRS Research Map | TGRS