Phytochemical assessment, and estimation of hypoglycemic potentials of the dichloromethane extract of Araucaria heterophylla leaves

Diabetes mellitus (DM), a chronic metabolic illness, is described by long term imbalance in glucose homeostasis. This study was carried out to identify the various phytochemicals, and to evaluate the hypoglycemic endeavor of crude dichloromethane extract of Araucaria heterophylla (A. heterphylla) leaves. Extraction was carried out using dichloromethane as a solvent. Preliminary phytochemical assessment of the crude dichloromethane extract of A. heterophylla (DAH) indicated the existence of diverse phytochemicals, including flavonoids, sterols, terpenoids, phenols, and carbohydrates. The DAH exhibited α-amylase inhibitory capacity comparable to that of the standard acarbose. Additionally, DAH effectively adsorbed glucose in both low, and high glucose concentrations used in the study.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-08-31
DOI
https://doi.org/10.5281/zenodo.17242860
Primary Topic
Economic and Technological Innovation
Type
article
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article

Phytochemical assessment, and estimation of hypoglycemic potentials of the dichloromethane extract of Araucaria heterophylla leaves

Zenodo (CERN European Organization for Nuclear Research)
Economic and Technological Innovation
article

Phytochemical assessment, and estimation of hypoglycemic potentials of the dichloromethane extract of Araucaria heterophylla leaves

article en

Abstract

Diabetes mellitus (DM), a chronic metabolic illness, is described by long term imbalance in glucose homeostasis. This study was carried out to identify the various phytochemicals, and to evaluate the hypoglycemic endeavor of crude dichloromethane extract of Araucaria heterophylla (A. heterphylla) leaves. Extraction was carried out using dichloromethane as a solvent. Preliminary phytochemical assessment of the crude dichloromethane extract of A. heterophylla (DAH) indicated the existence of diverse phytochemicals, including flavonoids, sterols, terpenoids, phenols, and carbohydrates. The DAH exhibited α-amylase inhibitory capacity comparable to that of the standard acarbose. Additionally, DAH effectively adsorbed glucose in both low, and high glucose concentrations used in the study.

Zenodo (CERN European Organization for Nuclear Research)
Good health and well-being
Openalex Percentile: Top 33%
Economic and Technological Innovation
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