Plant bioactives and nanotechnology: The new frontier for personalized dermatological treatment

odern dermatology relentlessly seeks more effective and safer solutions for skin care, driven by a growing demand for personalized approaches. This article explores the transformative synergy between plant-derived bioactives and nanotechnology, highlighting their potential to revolutionize individualized dermatological treatment. It discusses how <i>in vitro</i> plant cell culture offers a sustainable and controlled source of high-purity bioactives, overcoming limitations of traditional extraction methods. Subsequently, it addresses how nanotechnology optimizes the delivery, stability, and bioavailability of these plant compounds. Furthermore, the role of personalization, enabled by advancements in genomics, microbiome research, and artificial intelligence, in creating tailored skin therapies is analyzed. Regulatory, safety, and scalability challenges are examined, as are future prospects for this rapidly evolving field, which promises to redefine paradigms of skin health and beauty.