Case report: two cases of giant pelvic aggressive angiomyxoma

Aggressive angiomyxoma (AAM) is a rare mesenchymal tumor predominantly affecting females, with the pelvis being the common site. Surgery remains the primary treatment; however, its painless and slow-growing nature often delays early diagnosis, leading to large tumor size at presentation and challenges in achieving complete resection due to local invasiveness. This report describes two cases of giant pelvic AAM (maximum tumor diameter > 10 cm) managed at The Sixth Affiliated Hospital, Sun Yat-sen University. Based on the preoperative overall evaluation, one patient underwent tumor resection via a transsacral approach, while the other received combined abdominoperineal resection with urological collaboration. Both achieved favorable surgical outcomes.