Risk Of Obstructive Sleep Apnea Syndrome In An Adult Population With Hiv Infection In Southwest Nigeria

Background: Emerging data suggest that obstructive sleep apnea syndrome (OSAS) is common among people living with HIV (PLWH). The burden of HIV infection in Nigeria is high. Unrecognized and untreated OSAS have a significant impact on the quality of life and may affect the gains of successful treatment of HIV. The study was carried out to determine the proportion of an adult population of PLWH in South-western Nigeria who have a high risk for OSAS and the associated risk factors. Study design: A cross-sectional survey of 198 adults attending the clinic dedicated to PLWH at Bowen University Teaching Hospital (BUTH), Ogbomoso was done using the STOP-BANG questionnaire. Data collected include socio-demographic characteristics and anthropometric measurements. The blood pressure and BMI were measured and calculated respectively. Factors associated with high risk for OSAS were identified. Results: Of the 198 participants, 73.2% were females. Forty (20.2%) had a high risk for OSAS and the factors associated with this risk include male sex, age, BMI, neck circumference, hypertension and use of antiretroviral therapy (ART) regimen containing zidovudine (AZT) and protease inhibitors (PI). Duration on ART and CD4 count did not show a relationship with the risk of OSAS. Conclusion: The risk of OSAS is high in a significant proportion of an adult population of PLWH in South-western Nigeria and this risk is related to age, male sex, BMI, neck circumference, hypertension and use of ART regimen containing AZT and PI.