Smart Theranostic Platforms Based on Carbohydrate Hydrogels

Carbohydrate-based hydrogels represent a new advancement in the development of multifunctional biomedical systems, thanks to their intrinsic biocompatibility, structural versatility, and capacity for functional modification. This review examines the latest progress made in employing these materials as intelligent theranostic platforms, with a particular focus on their role as biosensors and therapeutic drug delivery devices. Engineered to interact dynamically with the biological environment, carbohydrate hydrogels enable the site-specific release of therapeutic agents while simultaneously supporting the monitoring of key physiological markers. Their dual functionality offers significant advantages in managing complex pathologies such as cancer, metabolic disorders, and chronic inflammation, where personalized treatment and real-time feedback are essential. By exploring their biological application, this review underscores the pivotal role played by carbohydrate hydrogels in advanced therapeutic technologies.

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Publication Details

Journal
Macromol—A Journal of Macromolecular Research
Published
2025-08-14
DOI
https://doi.org/10.3390/macromol5030037
Primary Topic
Diverse Scientific and Economic Studies
Type
article
Field-Weighted Citation Impact
0.00

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article

Smart Theranostic Platforms Based on Carbohydrate Hydrogels

Macromol—A Journal of Macromolecular Research
Diverse Scientific and Economic Studies
article

Smart Theranostic Platforms Based on Carbohydrate Hydrogels

article en

Abstract

Carbohydrate-based hydrogels represent a new advancement in the development of multifunctional biomedical systems, thanks to their intrinsic biocompatibility, structural versatility, and capacity for functional modification. This review examines the latest progress made in employing these materials as intelligent theranostic platforms, with a particular focus on their role as biosensors and therapeutic drug delivery devices. Engineered to interact dynamically with the biological environment, carbohydrate hydrogels enable the site-specific release of therapeutic agents while simultaneously supporting the monitoring of key physiological markers. Their dual functionality offers significant advantages in managing complex pathologies such as cancer, metabolic disorders, and chronic inflammation, where personalized treatment and real-time feedback are essential. By exploring their biological application, this review underscores the pivotal role played by carbohydrate hydrogels in advanced therapeutic technologies.

Macromol—A Journal of Macromolecular ResearchVol. 5(3)
University of Campania "Luigi Vanvitelli" (IT), Ospedale Santa Maria di Loreto Nuovo (IT), Saint Camillus International University of Health and Medical Sciences (IT), Technical University of Munich (DE), University of Palermo (IT)
European Commission
Good health and well-being
Openalex Percentile: Top 34%
Diverse Scientific and Economic Studies
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Smart Theranostic Platforms Based on Carbohydrate Hydrogels · Macromol—A Journal of Macromolecular Research (2025) | TGRS Research Map | TGRS