Case Report: Recurrent Miller Fisher Syndrome

We report the case of a 47-year-old male who presented with numbness and difficulty speaking and was diagnosed with Miller Fisher Syndrome, a variant Guillain-Barré Syndrome. The differential diagnosis for numbness and speech difficulty is broad and includes brain stem stroke, Wernicke encephalopathy, botulism, myasthenia gravis, among others. Although Miller Fisher Syndrome is rare, certain factors such as the of tumor necrosis factor-alpha antagonists may predispose a patient to the disease and its recurrence. As discovery of new tumor necrosis factor-alpha antagonists continues it will likely result in more presentations of Guillain-Barré Syndrome and its variants to the emergency department.

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Publication Details

Published
2025-05-01
DOI
https://doi.org/10.31986/issn.2689-0690_rdw.stratford_research_day.41_2025
Primary Topic
Helicobacter pylori-related gastroenterology studies
Type
article
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article

Case Report: Recurrent Miller Fisher Syndrome

Helicobacter pylori-related gastroenterology studies
article

Case Report: Recurrent Miller Fisher Syndrome

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Abstract

We report the case of a 47-year-old male who presented with numbness and difficulty speaking and was diagnosed with Miller Fisher Syndrome, a variant Guillain-Barré Syndrome. The differential diagnosis for numbness and speech difficulty is broad and includes brain stem stroke, Wernicke encephalopathy, botulism, myasthenia gravis, among others. Although Miller Fisher Syndrome is rare, certain factors such as the of tumor necrosis factor-alpha antagonists may predispose a patient to the disease and its recurrence. As discovery of new tumor necrosis factor-alpha antagonists continues it will likely result in more presentations of Guillain-Barré Syndrome and its variants to the emergency department.

Rowan University (US)
Openalex Percentile: Top 34%
Helicobacter pylori-related gastroenterology studies
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Case Report: Recurrent Miller Fisher Syndrome · (2025) | TGRS Research Map | TGRS