IDIOPATHIC INTRACRANIAL HYPERTENSION

Idiopathic intracranial hypertension (IIH) is a neurological disorder characterized by elevated intracranial pressure (ICP) due to accumulation of Cerebro spinal fluid (CSF) within the skull without an identifiable cause such as tumor or hydrocephalus. IIH is also known as pseudotumor cerebri. This condition mainly affected in women and obesity population. The exact etiology remains unclear but obesity, hormonal changes and medications like antibiotics are recognized as risk factors. IIH predominantly affects the brain and optic nerves, leading to symptoms such as headache, papilledema, visual disturbances which can result in permanent vision loss if untreated. Management strategies mainly focus on reducing ICP, maintaining eye vision and weight reduction. The first line therapy includes weight loss and medications like acetazolamide and Topiramate and in severe cases, surgical interventions including optic nerve sheath fenestration or CSF shunting. Lifestyle modifications, including weight loss through regular exercise, can be beneficial in managing patients with IIH. Early diagnosis and timely treatment are crucial to prevent irreversible visual impairment and improve patient outcomes.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-09-30
DOI
https://doi.org/10.5281/zenodo.17233895
Primary Topic
Silkworms and Sericulture Research
Type
article
Field-Weighted Citation Impact
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article

IDIOPATHIC INTRACRANIAL HYPERTENSION

Zenodo (CERN European Organization for Nuclear Research)
Silkworms and Sericulture Research
article

IDIOPATHIC INTRACRANIAL HYPERTENSION

article en

Abstract

Idiopathic intracranial hypertension (IIH) is a neurological disorder characterized by elevated intracranial pressure (ICP) due to accumulation of Cerebro spinal fluid (CSF) within the skull without an identifiable cause such as tumor or hydrocephalus. IIH is also known as pseudotumor cerebri. This condition mainly affected in women and obesity population. The exact etiology remains unclear but obesity, hormonal changes and medications like antibiotics are recognized as risk factors. IIH predominantly affects the brain and optic nerves, leading to symptoms such as headache, papilledema, visual disturbances which can result in permanent vision loss if untreated. Management strategies mainly focus on reducing ICP, maintaining eye vision and weight reduction. The first line therapy includes weight loss and medications like acetazolamide and Topiramate and in severe cases, surgical interventions including optic nerve sheath fenestration or CSF shunting. Lifestyle modifications, including weight loss through regular exercise, can be beneficial in managing patients with IIH. Early diagnosis and timely treatment are crucial to prevent irreversible visual impairment and improve patient outcomes.

Zenodo (CERN European Organization for Nuclear Research)
Gokula Krishna College of Pharmacy (IN)
Good health and well-being
Openalex Percentile: Top 42%
Silkworms and Sericulture Research
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