CURRENT AND EMERGING PHARMACOLOGICAL TREATMENT OPTIONS IN THE MANAGEMENT OF SUDDEN SENSORINEURAL HEARING LOSS

A fast decrease in hearing of 30 dB or more within 72 hours is known as Sudden Sensorineural Hearing Loss (SSNHL), which usually affects one or both ears and frequently manifests with no apparent explanation. This medical emergency has the potential to seriously harm social interaction, communication, and mental health. Although Sudden Sensorineural Hearing Loss is common, little is known about its origin, and there are few available treatments. Corticosteroids, which can be given orally or intratympanically, are the mainstay of current pharmacological therapy for inflammation reduction. Vasodilators like pentoxifylline and antiviral drugs like acyclovir have been studied, but their effectiveness is still up for debate. Although preliminary studies suggest potential benefits, further large-scale clinical trials are needed to establish the safety and efficacy of these emerging treatments. Investigational therapies such as gene editing and growth factor-based approaches offer hope for restoring hearing in patients with Sudden Sensorineural Hearing Loss. Continued research and clinical advancements are essential to refine these therapies and optimize their effectiveness in preventing permanent hearing loss and improving patient outcomes.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-09-30
DOI
https://doi.org/10.5281/zenodo.17233823
Primary Topic
Migration, Health and Trauma
Type
article
Field-Weighted Citation Impact
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article

CURRENT AND EMERGING PHARMACOLOGICAL TREATMENT OPTIONS IN THE MANAGEMENT OF SUDDEN SENSORINEURAL HEARING LOSS

Zenodo (CERN European Organization for Nuclear Research)
Migration, Health and Trauma
article

CURRENT AND EMERGING PHARMACOLOGICAL TREATMENT OPTIONS IN THE MANAGEMENT OF SUDDEN SENSORINEURAL HEARING LOSS

article en

Abstract

A fast decrease in hearing of 30 dB or more within 72 hours is known as Sudden Sensorineural Hearing Loss (SSNHL), which usually affects one or both ears and frequently manifests with no apparent explanation. This medical emergency has the potential to seriously harm social interaction, communication, and mental health. Although Sudden Sensorineural Hearing Loss is common, little is known about its origin, and there are few available treatments. Corticosteroids, which can be given orally or intratympanically, are the mainstay of current pharmacological therapy for inflammation reduction. Vasodilators like pentoxifylline and antiviral drugs like acyclovir have been studied, but their effectiveness is still up for debate. Although preliminary studies suggest potential benefits, further large-scale clinical trials are needed to establish the safety and efficacy of these emerging treatments. Investigational therapies such as gene editing and growth factor-based approaches offer hope for restoring hearing in patients with Sudden Sensorineural Hearing Loss. Continued research and clinical advancements are essential to refine these therapies and optimize their effectiveness in preventing permanent hearing loss and improving patient outcomes.

Zenodo (CERN European Organization for Nuclear Research)
Government Medical College (IN), Kerala University of Health Sciences (IN)
Openalex Percentile: Top 38%
Migration, Health and Trauma
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