Active Enhancers : Recent Research Advances and Insights into Disease

Development depends on the precise control of gene expression. The spatiotemporal Pattern of gene transcription is determined by Enhancers, which are at the heart of Gene control. The study of enhancers will yield hints for precise therapy because they Are known to include a large number of mutations linked to disease. Rapid Advancements in high-throughput sequencing technology make it easier to Characterize enhancers across the entire genome, yet it is still difficult to Comprehend how enhancers work. Here, we present a wide range of enhancer Attributes, such as enhancer-promoter interaction patterns, enhancer transcripts, And epigenetic changes. We also describe the use of functional genomics techniques and high-throughput sequencing technology in enhancer research. Lastly, we go over How enhancers contribute to human illness and how they might be targeted by Techniques for both disease prevention and treatment.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-09-29
DOI
https://doi.org/10.5281/zenodo.17226139
Primary Topic
Cutaneous Melanoma Detection and Management
Type
article
Field-Weighted Citation Impact
0.00
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article

Active Enhancers : Recent Research Advances and Insights into Disease

Zenodo (CERN European Organization for Nuclear Research)
Cutaneous Melanoma Detection and Management
article

Active Enhancers : Recent Research Advances and Insights into Disease

article en

Abstract

Development depends on the precise control of gene expression. The spatiotemporal Pattern of gene transcription is determined by Enhancers, which are at the heart of Gene control. The study of enhancers will yield hints for precise therapy because they Are known to include a large number of mutations linked to disease. Rapid Advancements in high-throughput sequencing technology make it easier to Characterize enhancers across the entire genome, yet it is still difficult to Comprehend how enhancers work. Here, we present a wide range of enhancer Attributes, such as enhancer-promoter interaction patterns, enhancer transcripts, And epigenetic changes. We also describe the use of functional genomics techniques and high-throughput sequencing technology in enhancer research. Lastly, we go over How enhancers contribute to human illness and how they might be targeted by Techniques for both disease prevention and treatment.

Zenodo (CERN European Organization for Nuclear Research)
Openalex Percentile: Top 37%
Cutaneous Melanoma Detection and Management
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