Scaling symmetry of the Hodgkin-Huxley mathematical model

A computational method based on the application of a scaling transformation to the Hodgkin-Huxley mathematical model of the biological neuron and its generalizations to the case of various neural systems is proposed. The method makes it possible: 1) to obtain invariants of the scaling transformation of the Hodgkin-Huxley model; 2) to find self-similarity regions corresponding to the modes of neural activity; 3) to determine the conditions for the similarity of models of various types of biological neurons; 4) to reduce the order of the system of differential equations of the Hodgkin-Huxley model for neural systems with synchronous activity. The capabilities of the method are demonstrated using various examples from neurobiology.

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Publication Details

Journal
UKnowledge (University of Kentucky)
Published
2025-09-29
DOI
https://doi.org/10.13023/psmij.2025.06-01-02
Primary Topic
Sociopolitical Dynamics in Nepal
Type
article
Field-Weighted Citation Impact
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article

Scaling symmetry of the Hodgkin-Huxley mathematical model

UKnowledge (University of Kentucky)
Sociopolitical Dynamics in Nepal
article

Scaling symmetry of the Hodgkin-Huxley mathematical model

article en

Abstract

A computational method based on the application of a scaling transformation to the Hodgkin-Huxley mathematical model of the biological neuron and its generalizations to the case of various neural systems is proposed. The method makes it possible: 1) to obtain invariants of the scaling transformation of the Hodgkin-Huxley model; 2) to find self-similarity regions corresponding to the modes of neural activity; 3) to determine the conditions for the similarity of models of various types of biological neurons; 4) to reduce the order of the system of differential equations of the Hodgkin-Huxley model for neural systems with synchronous activity. The capabilities of the method are demonstrated using various examples from neurobiology.

UKnowledge (University of Kentucky)
Samara State Medical University (RU)
Openalex Percentile: Top 29%
Sociopolitical Dynamics in Nepal
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