Towards a Unified Field Theory of Chemistry: Bridging Quantum, Organic, and Biochemical Reactions through a Single Formalism

This work introduces the Unified Field Theory of Chemistry (UFTC), a novel operator-based framework that bridges quantum, organic, and biochemical chemistry into a single coherent formalism. By integrating quantum mechanical foundations with organic reactivity rules and enzymatic catalysis, the UFTC enables both prediction and optimization of chemical reactions across scales. The methodology relies on universal operators for bond transformations, numerical solutions of Schrödinger-like equations for complex systems, and validation against experimental data. Applications include molecular discovery, green chemistry optimization, biochemical engineering, and integration with AI for high-throughput molecular prediction. Results demonstrate accurate reproduction of electron transfer rates, bond dissociation energies, regioselectivity in organic reactions, and enzyme-catalyzed activation energy reductions, aligning closely with experimental data. The UFTC therefore provides both a conceptual bridge across fragmented domains of chemistry and a practical tool for accelerating discovery in drug design, synthetic biology, and sustainable chemical engineering.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-09-28
DOI
https://doi.org/10.5281/zenodo.17217046
Primary Topic
Global Maternal and Child Health
Type
article
Field-Weighted Citation Impact
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article

Towards a Unified Field Theory of Chemistry: Bridging Quantum, Organic, and Biochemical Reactions through a Single Formalism

Zenodo (CERN European Organization for Nuclear Research)
Global Maternal and Child Health
article

Towards a Unified Field Theory of Chemistry: Bridging Quantum, Organic, and Biochemical Reactions through a Single Formalism

article en

Abstract

This work introduces the Unified Field Theory of Chemistry (UFTC), a novel operator-based framework that bridges quantum, organic, and biochemical chemistry into a single coherent formalism. By integrating quantum mechanical foundations with organic reactivity rules and enzymatic catalysis, the UFTC enables both prediction and optimization of chemical reactions across scales. The methodology relies on universal operators for bond transformations, numerical solutions of Schrödinger-like equations for complex systems, and validation against experimental data. Applications include molecular discovery, green chemistry optimization, biochemical engineering, and integration with AI for high-throughput molecular prediction. Results demonstrate accurate reproduction of electron transfer rates, bond dissociation energies, regioselectivity in organic reactions, and enzyme-catalyzed activation energy reductions, aligning closely with experimental data. The UFTC therefore provides both a conceptual bridge across fragmented domains of chemistry and a practical tool for accelerating discovery in drug design, synthetic biology, and sustainable chemical engineering.

Zenodo (CERN European Organization for Nuclear Research)
IndependenceFirst (US)
Responsible consumption and production
Openalex Percentile: Top 31%
Global Maternal and Child Health
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Towards a Unified Field Theory of Chemistry: Bridging Quantum, Organic, and Biochemical Reactions through a Single Formalism · Zenodo (CERN European Organization for Nuclear Research) (2025) | TGRS Research Map | TGRS