Frequency of Pregnancy related Acute Kidney Injury

Introduction: Acute kidney injury in pregnancy carries significant risk for maternal & fetal well-being. Over the last couple of decades the frequency of pregnancy related acute kidney injury has significantly reduced around the globe & especially in the developed world, owning to considerable improvement in ante-natal and overall health-care facilities. However, unlike the developed world, the prevalence of Pregnancy Related Acute Kidney Injury (PR-AKI) in the developing world is still high and in double digits in some of the underdeveloped countries due to poor health-care facilities pertinent to antenatal care. Methodology: This study has descriptive cross-sectional design. Therefore, considering the nature of empirical investigation, data was collected at Nephrology & Gynaecology & Obstetrics indoor and outdoor patient departments, Sheikh Zayed Medical College and teaching hospital, Rahim Yar Khan, from January 1 to 30, May 2025. A total number of 101 pregnant women were enrolled in the study using non-probability consecutive sampling, based on established inclusion and exclusion criteria. The Participants were monitored throughout pregnancy and up to six weeks postpartum to identify cases of PR-AKI. Results: The mean age of participants in the study was 25.35 ± 4.05 years. PR-AKI was diagnosed in 10 patients (9.9%), while the remaining 91 patients remained free of renal complications. The majority of acute kidney injury cases occurred due to late trimester or postpartum period complications, with postpartum hemorrhage identified as the most common contributing factor. Conclusion: The frequency of pregnancy-related acute kidney injury in this cohort was around 10%, with postpartum hemorrhage emerging as the predominant cause. Early identification and management of high-risk obstetric conditions may help reduce the burden of PR-AKI.