Diffuse Osteosclerosis in Metastatic Prostatic Cancer: The Plain Radiographic Findings and a Case Report

Abstract: Prostatic cancers commonly metastasize to bone, leading to either osteoblastic or osteolytic lesions. In cases of osteoblastic deposits; diffuse osteosclerosis may sometimes occur. Patients with diffuse osteosclerosis may have very high bone mineral density (BMD), which can be detected by bone density scans. This is a 65-year-old man with a diagnosis of prostatic cancer referred from a peripheral facility for chest and pelvic radiographs. The patient had complaints of severe pains involving almost all the bones in his body, this started from lower back and the pelvic bones with subsequent inability to move the limbs especially the left. The plain radiographs showed diffuse osteosclerosis to involve all the demonstrated bones with associated subtrochanteric fracture of the left femur. The patient’s total and free prostate specific antigen (PSA) were very high, the prostatic biopsy confirmed adenocarcinoma. We present a case of diffuse osteosclerosis in a confirmed case of prostatic cancer due to its peculiar presentation and to review the literature.