Evaluación de la actividad antimicrobiana del extracto alcohólico de Tagetes erecta contra bacterias y hongos de importancia clínica

Introduction: Antibiotic resistance is a significant global health concern, putting at risk treatment options for infectious diseases. As a result, treatments can be expensive and ineffective, so it is essential to look for new options such as the use of plant extracts with antimicrobial properties to combat these diseases. Tagetes sp is a plant species that is used in folk medicine to cure various diseases and has several properties among which the antimicrobial. Method: The antimicrobial activity of the extract was analyzed by the Kirby-Bauer method at different concentrations. Results: The extract showed antimicrobial activity by presenting inhibition halos mainly against Staphylococcus aureus (S. aureus), obtaining the following results: S. aureus ATCC 43300 (19,400 ± 0.435 mm to 500 mg/mL); S. aureus ATCC 6538 (11,206 ± 0.342 mm to 750 mg/mL); Acinetobacter baumannii ATCC 19606 (10.570 ± 0.535 mm a 250 mg/mL); Proteus mirabilis (7.636 ± 0.196 mm to 250 mg/mL) and Issatchenkia orientalis ATCC 6258 (7.400 ± 0.190 mm to 250 mg/mL). Secondary metabolites such as tannins, quinones, coumarins, phenolic compounds and flavonoids were determined. Conclusions: Tagetes erecta L alcoholic extract has antimicrobial activity against clinically relevant strains and may be considered for further studies against multi-resistant microorganisms in the future.