TO EVALUATE THE EFFICIENCY OF NANO-CURCUMIN ORAL ADMINISTRATION AS AN ADJUNCTIVE THERAPEUTIC APPROACH WITH SCALING AND ROOT PLANNING IN TREATMENT OF GINGIVITIS.

Abstract: Background: To evaluate the efficiency of nano-curcumin oral administration as an adjunctive therapeutic approach with scaling and root planning in the treatment of gingivitis. Methods: A total of 24 patients diagnosed with established gingivitis were divided into two groups with Group-I (n=12) are treated with Scaling and root planning along with oral administration of nanocurcumin capsules (500mg) once daily for 3 weeks and Group-II (n=12) were treated with Scaling and root planning with placebo capsules. Plaque index (PI), gingival index (GI), and sulcus bleeding index (SBI) were recorded at baseline and 3 weeks. Result: The mean score of PI, GI and SBI scores in Group I at baseline were 1.75 ± 0.30, 1.37 ± 0.38, and 2.06 ± 0.61. At 3 weeks the mean scores were reduced to 0.77 ± 0.22, 0.74 ± 0.28 and 0.98 ± 0.29 respectively. Similarly, the mean scores in Group II at baseline were 1.70 ± 0.32, 1.36 ± 0.43 and 1.91 ± 0.51, whereas at 3 weeks scores were reduced to 0.84 ± 0.81, 0.86 ± 0.33 and 1.13 ± 0.45. A statistically significant (P<0.001) reduction in PI, GI and SBI scores was observed in both the groups from baseline to 3 weeks. Intragroup comparison showed PI, GI and SBI scores were reduced at 3 weeks in Group II than Group I, which was not statistically significant. Conclusion: The use of nanocurcumin capsules was efficient in treating gingivitis by reducing its inflammatory components. Good patient acceptance was observed in Group I patients with use of nanocurcumin as adjunctive therapy. KEYWORDS: Gingivitis, Nanocurcumin, Scaling and Root planning