A PROSPECTIVE OBSERVATIONAL STUDY ON UTILIZATION OF ANTI- PLATELET DRUGS IN TERTIARY CARE HOSPITAL.

Objective: Our study aims to assess the use of different antiplatelet drugs in vascular diseases. The main objectives are to evaluate the drug use pattern of antiplatelets in tertiary care hospitals and to observe the drug interactions in patients administered with antiplatelet therapy. Methodology :It is a Prospective Observational study conducted over a period of six months in the Department of General Medicine at Osmania General Hospital. The Data was collected in a designed Data Collection, and the same Data is presented via Graphical Data Presentation (Bar Graph, Pie Chart). All patients were subjected to a complete medical history (risk factors, medications), thorough clinical examination, ECG, coronary angiography, and lab investigations. Results: The incidence of coronary artery disease, unstable angina, NSTEMI, and stroke was found in a total number of 100 patients, out of which 37% of patients are affected by ischemic stroke, 27% are affected with CAD, 19% are affected with unstable angina, and 17% with NSTEMI. The patients in the age group of 51–70 are mostly prescribed antiplatelet drugs. Among the study population, 80% of patients are prescribed dual antiplatelet therapy (DAPT) and 20% are prescribed monotherapy. Compliance with the European Society guidelines for prescribing antiplatelet drugs in tertiary care hospitals was estimated to be 89%, and the 11% non-compliance was due to drug interactions and a lack of education. Conclusion: In this study 100 cases of antiplatelet were recorded over a period of 6 months. As per the study conducted, the male population is predominantly with exposure to disease. Among the collected cases, it was recorded that most patients have co-morbidities such as diabetes mellitus (55%) and hypertension (45%). Among our patient's majority were suffering from Ischemic stroke, CAD, Unstable Angina, and NSTEMI. The most commonly prescribed drugs are Aspirin (80%) and clopidogrel (20%). Dual therapy was prescribed (80%). As per the investigational reports, which were done during the treatment of the patients, these included ECG and hematological examinations. Keywords: Ischemic heart disease, Angiography, ST elevation Myocardial infarction, Myocardial Infarction, , Coronary Artery Disease.