DİYAFRAM TONUS BOZUKLUKLARI

The diaphragm, a dome-shaped musculo-fibrous structure separating the thoracic and abdominal cavities, is recognized as the primary muscle of respiration and an indispensable organ for life. Thanks to the unique composition of its muscle fibers and neural innervation, it plays a critical role in both resting and forced breathing. The electrical activity of the diaphragm can be monitored using neurophysiological techniques, serving as an important indicator for personalized ventilatory support adjustments. However, various pathological conditions—affecting the nerves, muscles, or neuromuscular junction—lead to diaphragmatic dysfunction, which may cause dyspnea, exercise intolerance, and respiratory failure. Different forms of dysfunction such as congenital eventration, paralysis, spasticity, and myoclonus contribute to impaired respiratory functions and reduced quality of life. Particularly in neurological diseases, diaphragmatic spasticity negatively impacts ventilatory efficiency by limiting muscle contraction capacity. This review comprehensively discusses the anatomical and physiological features of the diaphragm, methods for assessing its electrical activity, and the clinical implications of its dysfunctions. It highlights the importance of a multidisciplinary approach for preserving diaphragm health and effectively managing related diseases.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-09-24
DOI
https://doi.org/10.5281/zenodo.17192372
Primary Topic
Health, Medicine and Society
Type
article
Field-Weighted Citation Impact
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article

DİYAFRAM TONUS BOZUKLUKLARI

Zenodo (CERN European Organization for Nuclear Research)
Health, Medicine and Society
article

DİYAFRAM TONUS BOZUKLUKLARI

article en

Abstract

The diaphragm, a dome-shaped musculo-fibrous structure separating the thoracic and abdominal cavities, is recognized as the primary muscle of respiration and an indispensable organ for life. Thanks to the unique composition of its muscle fibers and neural innervation, it plays a critical role in both resting and forced breathing. The electrical activity of the diaphragm can be monitored using neurophysiological techniques, serving as an important indicator for personalized ventilatory support adjustments. However, various pathological conditions—affecting the nerves, muscles, or neuromuscular junction—lead to diaphragmatic dysfunction, which may cause dyspnea, exercise intolerance, and respiratory failure. Different forms of dysfunction such as congenital eventration, paralysis, spasticity, and myoclonus contribute to impaired respiratory functions and reduced quality of life. Particularly in neurological diseases, diaphragmatic spasticity negatively impacts ventilatory efficiency by limiting muscle contraction capacity. This review comprehensively discusses the anatomical and physiological features of the diaphragm, methods for assessing its electrical activity, and the clinical implications of its dysfunctions. It highlights the importance of a multidisciplinary approach for preserving diaphragm health and effectively managing related diseases.

Zenodo (CERN European Organization for Nuclear Research)
Mudanya Üniversitesi, Pamukkale University (TR)
Openalex Percentile: Top 34%
Health, Medicine and Society
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