Alternative Methods of Animal Models Testing

It has long been common practice to employ animal models in scientific study and medicine development. However, a quest for other strategies has been spurred by ethical issues, animal welfare, and the growing need for more precise and efficient testing techniques. Several possible substitutes for animal testing have surfaced in recent years, including as 3D bioprinting, organ-on-chip technologies, in vitro cell-based tests, and computer modeling. By minimizing the need for animal testing and increasing the relevance and repeatability of results, these alternatives have the potential to provide more accurate models of human physiology and illness. High-throughput drug screening is possible in vitro utilizing human-derived cell lines, while organ-on-chip technologies provide a more realistic representation of human reactions by simulating intricate tissue interactions. Furthermore, sophisticated computer models are able to forecast.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-09-24
DOI
https://doi.org/10.5281/zenodo.17193496
Primary Topic
Geochemistry and Geologic Mapping
Type
article
Field-Weighted Citation Impact
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article

Alternative Methods of Animal Models Testing

Zenodo (CERN European Organization for Nuclear Research)
Geochemistry and Geologic Mapping
article

Alternative Methods of Animal Models Testing

article en

Abstract

It has long been common practice to employ animal models in scientific study and medicine development. However, a quest for other strategies has been spurred by ethical issues, animal welfare, and the growing need for more precise and efficient testing techniques. Several possible substitutes for animal testing have surfaced in recent years, including as 3D bioprinting, organ-on-chip technologies, in vitro cell-based tests, and computer modeling. By minimizing the need for animal testing and increasing the relevance and repeatability of results, these alternatives have the potential to provide more accurate models of human physiology and illness. High-throughput drug screening is possible in vitro utilizing human-derived cell lines, while organ-on-chip technologies provide a more realistic representation of human reactions by simulating intricate tissue interactions. Furthermore, sophisticated computer models are able to forecast.

Zenodo (CERN European Organization for Nuclear Research)
Openalex Percentile: Top 28%
Geochemistry and Geologic Mapping
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