Design, Formulation, And Pharmacological Evaluation of Novel Lipid-Based Nanocarriers for Targeted Delivery of Synthesized Anti-Inflammatory Agents

Novel drug delivery systems have paved the way for nano- and micro-formulation techniques, addressing the challenges of poorly soluble and permeable drugs. Among these, lipid-based nanoparticles, such as liposomes, niosomes, and micelles, have gained widespread acceptance and are FDA-approved. These lipid-based systems are particularly beneficial for delivering natural phytoconstituents and enhancing the solubility, permeability, and bioavailability of drugs, especially those classified under BCS Class II and Class IV. This article reviews recent developments and applications of lipid-based dosage forms in improving therapeutic efficacy.