IMPACT OF INTRACANAL MEDICAMENTS ON PERIAPICAL PH AND THEIR BEHAVIOR IN ACIDIC ENVIRONMENTS: AN IN VITRO ANALYSIS

The purpose of this in vitro study was to test the pH changes that occurred over a period of 7 days using calcium hydroxide, Metapex and Ledermix & Calcium hydroxide combination and to compare the effect of contamination in a simulated periapical environment. The materials were filled in extracted premolar roots, which were suspended in individual vials containing distilled water at a pH of 7.4. Digital pH-meter was used to measure the pH of different groups at half an hr, 1 hr, 4 hr, 1 day, 2 days 3 days & 7 days after immersion of the specimens. The mean pH was found for all groups and statistical analysis was carried out using repeated Measure ANOVA. Combination of medicaments did affect the pH of calcium hydroxide significantly. Calcium hydroxide was found to significantly raise the pH of the surrounding medium with and without contamination of root canals compared to combination medicaments. Therefore calcium hydroxide is an effective choice in clinical practice where seepage of pus into the root canal between appointments

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-09-24
DOI
https://doi.org/10.5281/zenodo.17191209
Primary Topic
Gynecological conditions and treatments
Type
article
Field-Weighted Citation Impact
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article

IMPACT OF INTRACANAL MEDICAMENTS ON PERIAPICAL PH AND THEIR BEHAVIOR IN ACIDIC ENVIRONMENTS: AN IN VITRO ANALYSIS

Zenodo (CERN European Organization for Nuclear Research)
Gynecological conditions and treatments
article

IMPACT OF INTRACANAL MEDICAMENTS ON PERIAPICAL PH AND THEIR BEHAVIOR IN ACIDIC ENVIRONMENTS: AN IN VITRO ANALYSIS

article en

Abstract

The purpose of this in vitro study was to test the pH changes that occurred over a period of 7 days using calcium hydroxide, Metapex and Ledermix & Calcium hydroxide combination and to compare the effect of contamination in a simulated periapical environment. The materials were filled in extracted premolar roots, which were suspended in individual vials containing distilled water at a pH of 7.4. Digital pH-meter was used to measure the pH of different groups at half an hr, 1 hr, 4 hr, 1 day, 2 days 3 days & 7 days after immersion of the specimens. The mean pH was found for all groups and statistical analysis was carried out using repeated Measure ANOVA. Combination of medicaments did affect the pH of calcium hydroxide significantly. Calcium hydroxide was found to significantly raise the pH of the surrounding medium with and without contamination of root canals compared to combination medicaments. Therefore calcium hydroxide is an effective choice in clinical practice where seepage of pus into the root canal between appointments

Zenodo (CERN European Organization for Nuclear Research)
Government Dental College & Research Institute (IN), JSS Dental College and Hospital (IN)
Clean water and sanitation
Openalex Percentile: Top 35%
Gynecological conditions and treatments
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IMPACT OF INTRACANAL MEDICAMENTS ON PERIAPICAL PH AND THEIR BEHAVIOR IN ACIDIC ENVIRONMENTS: AN IN VITRO ANALYSIS · Zenodo (CERN European Organization for Nuclear Research) (2025) | TGRS Research Map | TGRS