Predictive factors for successful labor induction in women with premature rupture of membranes: a retrospective analysis

Premature rupture of membranes (PROM) is a significant complication that affects perinatal outcomes, particularly in preterm pregnancies. PROM has serious consequences for both maternal and fetal health, as it disrupts the essential physiological role of amniotic fluid in protecting the fetus and supporting its development, while also increasing the risk of infections and other complications. In modern perinatology, this issue is one of the leading causes of preterm birth and perinatal mortality. Induction of labor in the case of PROM is an important measure to minimize the risk of infections and complications for both the mother and the child. However, the success of this process depends on numerous factors, including the condition of both the mother and the fetus. Aim - to identify the key factors influencing the effectiveness of labor induction in women with premature rupture of membranes (PROM) and assess their impact on the success of the induction. Materials and methods. A retrospective analysis was conducted on 79 clinical cases of pregnant women with PROM. Parameters such as age, body mass index (BMI), and fetal weight were considered in the study. Logistic regression analysis was used to assess the predictive factors for successful labor induction. Results. It was established that a higher BMI, greater fetal weight, and maternal age were associated with a decreased likelihood of successful labor induction. The obtained data were confirmed by logistic regression analysis, indicating a significant impact of these factors on the prediction of induction outcomes. Conclusions. Age, BMI, and fetal weight are key risk factors for unsuccessful labor induction in women with PROM. The results can be used to provide a personalized approach to managing such patients and optimizing labor management strategies. This study was conducted in accordance with the principles of the Declaration of Helsinki. The study protocol was approved by the local ethics committee of the institution. Informed consent was obtained from all patients. The authors declare no conflict of interest.