The Dublin lens: a Cc = 1.0 mm objective lens intended for CryoEM at 100 keV
Abstract We have designed, fabricated and tested a lens with a chromatic aberration coefficient (Cc) of 1.0 mm, a 4.0 mm pole-gap and 2.0 mm bore that is wide enough to accommodate an anti-contamination system and an objective aperture. This lens extends the temporal-coherence envelope of the electron microscope beyond 2 Å, using a low-cost Schottky FEG. We hope that this lens design can be used to improve all 100 keV electron microscopes designed for single-particle electron cryomicroscopy (cryoEM).
Institutions
- MRC Laboratory of Molecular Biology (GB)
- Trinity College Dublin (IE)
- Turbo Power Systems (United Kingdom) (GB)
- Advanced Materials and BioEngineering Research (IE)
- Tris Pharma (United States) (US)
- University of York (GB)
Publication Details
- Journal
- Methods in microscopy
- Published
- 2025-09-23
- DOI
- https://doi.org/10.1515/mim-2025-0019
- Citations
- 1
- Primary Topic
- Agriculture, Land Use, Rural Development
- Type
- article
- Field-Weighted Citation Impact
- 4.83