Pharmacognostic Evaluation and Antioxidant Potential of Celtis integrifolia Leaves

Background: Celtis integrifolia Lam is commonly known as hackberry or nettle tree from the family of Ulmaceae. It’s renowned for its medicinal properties having a history of traditional use. This study aimed to investigate some pharmacognostic characteristics, phytochemical constituents and antioxidant potential of the leaves of C. integrifolia. Methods: Pharmacognostic standardization of the leaf was assessed based on the chemomicroscopic and some physicochemical parameters. The powdered leaf was extracted using methanol, concentrated and used for the phytochemical analysis and antioxidant assays. Results: The chemomicroscopy evaluation showed the presence of Cellulose, lignified cell wall, calcium oxalate, inulin and tannin. Physicochemical parameters such as moisture content/loss on drying (6.59 %), total ash value (21.93%), acid insoluble ash (14.1%), water-insoluble ash (17.5%) and water had high extractive value of (17.1%) compared to methanol which had extractive value (10%). Qualitative phytochemical analysis of methanol extract of C. integrifolia leaves revealed the presence of carbohydrate, flavonoids, steroids, cardiac glycoside, tritepenes, tannins, alkaloids and saponins. The methanol extract of C. integrifolia leaves demonstrated antioxidant activity. Conclusion: The Pharmacognostic parameters observed in this study will be of help in correct identification and quality control of C. integrifolia. The presence of bioactive chemicals and exhibition of antioxidant activity of C. integrifolia leaves justified its uses the traditional medicine.