A DESCRIPTIVE STUDY ON HISTOPATHOLOGICAL SPECTRUM AND CLINICAL PROFILE OF PATIENTS WITH MALIGNANT OVARIAN TUMOUR AT MEDICAL COLLEGE KOLKATA, WEST BENGAL

Introduction: Ovarian cancer is the sixth most common cancer in women and the second most common gynecological malignancy, accounting for 4% of all female cancers and 235 of gynecological cancers worldwide. One in 78 women is at risk of developing ovarian cancer, and 1 in 108 may die from it. Aims: To analyze the clinical profile and histopathological patterns of ovarian malignancies and assess their distribution in different socio-economic groups. Materials & Methods: An institution-based observational study was conducted from November 2022- April 2024 at Department of Gynaecology and Obstetrics in Medical college and Hospital, Kolkata, India. Results: Among patients, 6 (11.3%) had Irregular, 37 (69.8%) were Postmenopausal, and 10 (18.9%) had Regular Menstrual History. Serous carcinoma was the most common subtype, followed by mucinous and endometrioid. A statistically significant association was found between ovarian cancer and family history (z = 6.1321, p is <0.00001). Conclusion: Ovarian malignancies show varied histopathological subtypes, with serous carcinoma predominating. Postmenopausal status was the most frequent clinical profile. Family history in first-degree relatives was rare but statistically significant.