MRI as a Monitoring Tool for Detecting Therapeutic Response in the Recurrence of Carcinoma Cervix

Background: Carcinoma cervix recurrence is difficult to assess clinically, and MRI offers superior soft tissue evaluation. Methods: A hospital-based observational study was conducted on 44 post-treatment cases using T2W, DWI, and contrast MRI sequences. Clinical findings were correlated with imaging to determine diagnostic accuracy. Results: MRI identified 22 recurrent lesions, including cases missed clinically. Sensitivity, specificity, and accuracy were 88.89%, 30%, and 57.89% respectively. The T2W+DWI combination diagnosed all recurrences and excluded false positives, while contrast had limited added value. MRI also detected nodal recurrence in one case without a pelvic mass. Conclusion: MRI, especially T2W with DWI, is a reliable tool for post-treatment surveillance of carcinoma cervix, aiding early detection of recurrence and avoiding overtreatment.

Publication Details

Journal
Journal of Carcinogenesis
Published
2025-09-20
DOI
https://doi.org/10.64149/j.carcinog.24.5s.717-720
Primary Topic
Geochemistry and Geologic Mapping
Type
article
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article

MRI as a Monitoring Tool for Detecting Therapeutic Response in the Recurrence of Carcinoma Cervix

Journal of Carcinogenesis
Geochemistry and Geologic Mapping
article

MRI as a Monitoring Tool for Detecting Therapeutic Response in the Recurrence of Carcinoma Cervix

article en

Abstract

Background: Carcinoma cervix recurrence is difficult to assess clinically, and MRI offers superior soft tissue evaluation. Methods: A hospital-based observational study was conducted on 44 post-treatment cases using T2W, DWI, and contrast MRI sequences. Clinical findings were correlated with imaging to determine diagnostic accuracy. Results: MRI identified 22 recurrent lesions, including cases missed clinically. Sensitivity, specificity, and accuracy were 88.89%, 30%, and 57.89% respectively. The T2W+DWI combination diagnosed all recurrences and excluded false positives, while contrast had limited added value. MRI also detected nodal recurrence in one case without a pelvic mass. Conclusion: MRI, especially T2W with DWI, is a reliable tool for post-treatment surveillance of carcinoma cervix, aiding early detection of recurrence and avoiding overtreatment.

Journal of CarcinogenesisVol. 24(5s)
Good health and well-being
Openalex Percentile: Top 31%
Geochemistry and Geologic Mapping
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