Intrahepatic cholestasis of pregnancy: A case report

Intrahepatic cholestasis of pregnancy is the most common liver disease that occurs exclusively during pregnancy. Its development poses a potential risk to the mother, but especially to the fetus, and requires appropriate management and follow-up. The clinical presentation is characterized by pruritus and elevation of bile acid concentration, but there may be alterations in hepatic biochemical parameters, leading to a thorough differential diagnosis to rule out other liver diseases that may occur during pregnancy. We present the case of a pregnant woman who presented with pruritus since the end of the first trimester with the finding of elevated bile acid concentration in the moderate range and in whom other possible causes of liver involvement were ruled out.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-03-30
DOI
https://doi.org/10.5281/zenodo.17173258
Primary Topic
Geochemistry and Geologic Mapping
Type
article
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article

Intrahepatic cholestasis of pregnancy: A case report

Zenodo (CERN European Organization for Nuclear Research)
Geochemistry and Geologic Mapping
article

Intrahepatic cholestasis of pregnancy: A case report

article en

Abstract

Intrahepatic cholestasis of pregnancy is the most common liver disease that occurs exclusively during pregnancy. Its development poses a potential risk to the mother, but especially to the fetus, and requires appropriate management and follow-up. The clinical presentation is characterized by pruritus and elevation of bile acid concentration, but there may be alterations in hepatic biochemical parameters, leading to a thorough differential diagnosis to rule out other liver diseases that may occur during pregnancy. We present the case of a pregnant woman who presented with pruritus since the end of the first trimester with the finding of elevated bile acid concentration in the moderate range and in whom other possible causes of liver involvement were ruled out.

Zenodo (CERN European Organization for Nuclear Research)
Universidad Libre de Colombia (CO)
Good health and well-being
Openalex Percentile: Top 31%
Geochemistry and Geologic Mapping
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