MOXIFLOXACIN AND ITS USE IN ODONTOGENIC INFECTIONS. AN ALTERNATIVE FOR PATIENTS WITH PENICILLIN ALLERGIES? LITERATURE REVIEW

Maxillofacial infections of odontogenic origin are a frequent cause of dental emergencies, primarily caused by caries, periodontal disease, and dentoalveolar abscesses. These infections, which can vary in severity and spread throughout facial spaces, sometimes require surgical management and intravenous drug treatment in hospitals. The oral bacterial flora is predominantly polymicrobial, with a majority of streptococci and the presence of staphylococci and anaerobic bacteria. Regarding antimicrobial treatment, penicillins (PEN) continue to be accepted as the first-line option, growing resistance has prompted the search for alternatives such as clindamycin and quinolones, with moxifloxacin being particularly notable for its broad spectrum and effectiveness against oral pathogens. This study evaluates the in vitro and in vivo efficacy of moxifloxacin in the treatment of maxillofacial infections, including maxillary sinusitis, abscesses, and cellulitis of odontogenic origin.