Thermal decomposition of 3-butyl-2,6-bis(4-fluorophenyl)piperidin-4-one in nitrogen atmosphere-Non-isothermal condition

 The compound 3-butyl-2,6-bis(4-fluorophenyl)piperidin-4-one was synthesized by refluxed with ammonium acetate, 2-heptanone and 4-flurobenzaldehyde using distilled ethanol. The synthesized product was characterized using FT-IR and NMR spectroscopy. Its thermal behavior was examined through decomposition studies carried out with a system integrating thermogravimetric analysis (TG), differential thermal analysis (DTA) and differential thermogravimetric analysis (DTG) under a dynamic nitrogen atmosphere over a range of temperatures. Kinetic and thermodynamic parameters were determined using iso-conversional model-free approaches, including the Friedman, Flynn-Wall-Ozawa (FWO) and Kissinger-Akahira-Sunose (KAS) methods. For model-fitting analysis, the Coats-Redfern method was employed. The TG curves revealed a single-step decomposition process. Activation energy (Ea) values and correlation coefficients (r) were obtained and graphically represented based on the isoconversional methods. Comparison of the theoretical reaction models with experimental results indicated that the compound decomposes according to a two-dimensional diffusion mechanism (F3 model). The derived kinetic and thermodynamic parameters were systematically summarized in tabulated form and illustrated through graphical plots.