On the Estimation of Heterogeneous Functional Treatment Effects

This work addresses the estimation of the Functional Conditional Average Treatment Effect (F-CATE ) – that is, the causal effect of a treatment on a functional outcome, conditional on covariates – in the framework of Functional Data Analysis (FDA). The objective is to uncover how treatment effects evolve over time and vary across levels of observed characteristics, a central challenge in modern causal inference with functional responses. To tackle this problem, we propose a novel class of functional meta-learners, specifically adapting R- and DR-learners to the functional setting, and emphasizing doubly robust (DR) approaches that combine outcome regression and propensity modeling to obtain unbiased estimators, even under partial mis-specification. Our methodology is grounded in a rigorous theoretical analysis, providing convergence guarantees and mathematical justification for the robustness properties of the estimators. We conduct extensive simulation studies to assess performance under various nuisance function mis- specification scenarios, illustrating the double robustness of the DR-learner: accurate recovery of F-CATE is achieved as long as either the propensity model or the outcome model is correctly specified. Finally, we apply our estimators to real-world data from the Survey of Health, Ageing and Retirement in Europe (SHARE), evaluating the causal effect of chronic medical conditions on the quality-of-life trajectories of older adults. The analysis controls for a rich set of covariates and provides visualizations of treatment effects across different subpopulations. Results demonstrate the practical value of functional meta-learners in capturing treatment heterogeneity over time.

Publication Details

Journal
Electronic Theses and Dissertations Repository (University of Pisa)
Published
2025-07-13
Primary Topic
Geochemistry and Geologic Mapping
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

On the Estimation of Heterogeneous Functional Treatment Effects

Electronic Theses and Dissertations Repository (University of Pisa)
Geochemistry and Geologic Mapping
article

On the Estimation of Heterogeneous Functional Treatment Effects

article en

Abstract

This work addresses the estimation of the Functional Conditional Average Treatment Effect (F-CATE ) – that is, the causal effect of a treatment on a functional outcome, conditional on covariates – in the framework of Functional Data Analysis (FDA). The objective is to uncover how treatment effects evolve over time and vary across levels of observed characteristics, a central challenge in modern causal inference with functional responses. To tackle this problem, we propose a novel class of functional meta-learners, specifically adapting R- and DR-learners to the functional setting, and emphasizing doubly robust (DR) approaches that combine outcome regression and propensity modeling to obtain unbiased estimators, even under partial mis-specification. Our methodology is grounded in a rigorous theoretical analysis, providing convergence guarantees and mathematical justification for the robustness properties of the estimators. We conduct extensive simulation studies to assess performance under various nuisance function mis- specification scenarios, illustrating the double robustness of the DR-learner: accurate recovery of F-CATE is achieved as long as either the propensity model or the outcome model is correctly specified. Finally, we apply our estimators to real-world data from the Survey of Health, Ageing and Retirement in Europe (SHARE), evaluating the causal effect of chronic medical conditions on the quality-of-life trajectories of older adults. The analysis controls for a rich set of covariates and provides visualizations of treatment effects across different subpopulations. Results demonstrate the practical value of functional meta-learners in capturing treatment heterogeneity over time.

Electronic Theses and Dissertations Repository (University of Pisa)
Openalex Percentile: Top 32%
Geochemistry and Geologic Mapping
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.