Exploring the Potential of Topical Drug Delivery System: A Systematic Review

Drug delivery systems are essential for ensuring medications effectively reach their target areas within the body. These systems employ various methods to introduce drugs and guide them to specific sites while balancing therapeutic effectiveness with distribution convenience. Many companies specializein developing and selling these systems, while others are proprietary and patented. Precision in dosage is crucial for proper medication absorption, requiring delivery systems that offer exact dosing. They must also consider the body's metabolism, as some drugs are broken down in the digestive system, rendering oral delivery ineffective. Time-release mechanisms are vital to prevent overdose risks, prioritizing patient safety. Topical drug delivery methods, such as skin patches, allow for medication to be absorbed through the body’s surface. Other methods include inhalable aerosols, eye drops, skin lotions, and nasal sprays. These methods are favored for their simplicity and ease of use for patients. The goal of any drug delivery system is to ensure the correct dose reaches the right location. Many drugs are available in both topical and enteral forms, applied externally or ingested, as patients often prefer non-invasive, pain-free options. However, in clinical settings, parenteral methods are preferred for their greater control over drug administration timing and dosage, particularly for regulated medications.