A review on immunity through stress reduction and positive mindset

The intricate network of cells and processes that makes up the immune system is a vital first line of defense against dangerous infections. This review explores the complex relationships that exist between immunity, stress, and psychological resilience, emphasizing the role that stress management and an optimistic outlook have in influencing immune function. An adaptable collection of mental and affective functions known as the Behavioral Immune System (BIS) aids in avoiding possible infection sources. Acute stress can momentarily stimulate immune function, but chronic stress results in immunological dysregulation, protracted inflammation, and heightened disease risk. A major risk factor for long-term immunological alterations, such as elevated inflammatory markers and the reactivation of dormant viruses, is early life stress (ELS). Optimism, good affect, and a sense of purpose in life are all components of positive psychological well-being (PPWB), which is linked to better immunological responses and better health outcomes. While optimism's impacts on immune function can vary depending on the context of stressors, it does seem to improve health-promoting behaviors and adaptive coping mechanisms. In order to lessen the negative effects of stress and increase immunological resilience, the review highlights the significance of including psychological therapies. Reducing stress-related health risks and enhancing general well-being may be greatly aided by the development of techniques that encourage optimistic thinking and emotional resilience.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-03-30
DOI
https://doi.org/10.5281/zenodo.17163411
Primary Topic
Geochemistry and Geologic Mapping
Type
article
Field-Weighted Citation Impact
0.00
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article

A review on immunity through stress reduction and positive mindset

Zenodo (CERN European Organization for Nuclear Research)
Geochemistry and Geologic Mapping
article

A review on immunity through stress reduction and positive mindset

article en

Abstract

The intricate network of cells and processes that makes up the immune system is a vital first line of defense against dangerous infections. This review explores the complex relationships that exist between immunity, stress, and psychological resilience, emphasizing the role that stress management and an optimistic outlook have in influencing immune function. An adaptable collection of mental and affective functions known as the Behavioral Immune System (BIS) aids in avoiding possible infection sources. Acute stress can momentarily stimulate immune function, but chronic stress results in immunological dysregulation, protracted inflammation, and heightened disease risk. A major risk factor for long-term immunological alterations, such as elevated inflammatory markers and the reactivation of dormant viruses, is early life stress (ELS). Optimism, good affect, and a sense of purpose in life are all components of positive psychological well-being (PPWB), which is linked to better immunological responses and better health outcomes. While optimism's impacts on immune function can vary depending on the context of stressors, it does seem to improve health-promoting behaviors and adaptive coping mechanisms. In order to lessen the negative effects of stress and increase immunological resilience, the review highlights the significance of including psychological therapies. Reducing stress-related health risks and enhancing general well-being may be greatly aided by the development of techniques that encourage optimistic thinking and emotional resilience.

Zenodo (CERN European Organization for Nuclear Research)
Openalex Percentile: Top 33%
Geochemistry and Geologic Mapping
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