Extragenital Donovanosis with late diagnosis. A case report

Background: Donovanosis is an infection caused by Klebsiella granulomatis, which produces genital ulcers. However, it also has various forms of presentation and can sometimes cause rare conditions such as extragenital or systemic presentation. Although it is very rare, it can transform malignantly into squamous cell carcinoma. This pathology was described in 1882 by McLeod, and in 1905, Charles Donovan identified the causal agent of the disease. This microorganism was initially considered a protozoan, but it was later discovered to be a bacterium. We report a clinical case of extragenital donovanosis treated at the New General Hospital of Gómez Palacio Durango, treated successfully with antibiotic therapy. Donovanosis is a rare disease. Mainly endemic in countries such as Papua New Guinea, South Africa, parts of India and Brazil, and among the Aboriginal community of Australia, sporadic cases have also been reported in other South American countries. Given its low frequency, it is important to be aware of this disease in order to make a timely diagnosis and treatment. Keywords: Granuloma Inguinale, Calymmatobacterium

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-09-20
DOI
https://doi.org/10.5281/zenodo.17163740
Primary Topic
Hip and Femur Fractures
Type
article
Field-Weighted Citation Impact
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article

Extragenital Donovanosis with late diagnosis. A case report

Zenodo (CERN European Organization for Nuclear Research)
Hip and Femur Fractures
article

Extragenital Donovanosis with late diagnosis. A case report

article en

Abstract

Background: Donovanosis is an infection caused by Klebsiella granulomatis, which produces genital ulcers. However, it also has various forms of presentation and can sometimes cause rare conditions such as extragenital or systemic presentation. Although it is very rare, it can transform malignantly into squamous cell carcinoma. This pathology was described in 1882 by McLeod, and in 1905, Charles Donovan identified the causal agent of the disease. This microorganism was initially considered a protozoan, but it was later discovered to be a bacterium. We report a clinical case of extragenital donovanosis treated at the New General Hospital of Gómez Palacio Durango, treated successfully with antibiotic therapy. Donovanosis is a rare disease. Mainly endemic in countries such as Papua New Guinea, South Africa, parts of India and Brazil, and among the Aboriginal community of Australia, sporadic cases have also been reported in other South American countries. Given its low frequency, it is important to be aware of this disease in order to make a timely diagnosis and treatment. Keywords: Granuloma Inguinale, Calymmatobacterium

Zenodo (CERN European Organization for Nuclear Research)
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Hip and Femur Fractures
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