Polypoid Presentation of Neuroendocrine Tumour of Stomach: A Case Report

Neuroendocrine Neoplasms (NENs) are rare epithelial tumours with neuroendocrine differentiation. We report a case of a 35-yearold female presenting with abdominal pain, haematemesis, and melena for four months. Clinical examination revealed generalised tenderness. Endoscopic Ultrasound (EUS) showed a well-defined, hyperechoic lesion in the third to fourth gastric wall layers, and Fine-Needle Aspiration Biopsy (FNAB) confirmed a well-differentiated Neuroendocrine Tumour (NET G2). Ga-68 DOTATATE Positron Emission Tomography-Computed Tomography (PET-CT) demonstrated a polyp on the posterior wall of the stomach with intense somatostatin receptor expression, localised to the gastric lesion with no evidence of distant metastasis. The patient underwent laparoscopic wide local excision with intraoperative endoscopic tumour localisation. Histopathology confirmed a welldifferentiated NET. Gastric NETs, especially in young adults, are rare, and early multimodal diagnosis using imaging, histopathology, and molecular markers is crucial. This case underscores the importance of a multidisciplinary approach for effective management and the potential for positive outcomes in localised gastric NETs.