AAAAI/WAO 2025 meeting update: Climate change, asthma, artificial intelligence, food allergy, and immunotherapy

AAAAI/WAO Joint Congress was held in San Diego, California from February 28 to March 3, 2025. The meeting theme of the year was “Climate Change and Allergic Diseases: Global Impact on Health”. This theme carried not just the weight of science, but also a sense of urgency in a world in the midst of change from many perspectives, not just scientific but also political and sociological. Other hot topics included “The Role of Artificial Intelligence and Informatics in the Detection and Management of Allergic Disorders” and “Asthma Management in an Ever-Changing World”. In the area of food allergy, a report on OUtMATCH was presented, focusing on the outcome of Omalizumab vs multi-food Oral Immunotherapy. An update on the new Immunotherapy Practice Parameter (2024) provided information on next-generation allergen immunotherapy. These topics are not independent of each other, illustrating the complex nature of our specialty. For example, climate change can affect air pollution, leading to increased asthma prevalence. This affects strategies for developing new asthma treatment algorithms, potentially leveraging artificial intelligence to optimize outcomes. Artificial intelligence is poised to transform our lives, not just in asthma management, but all across all areas of healthcare. Climate change will also impact how we treat food allergies due to the impact of microbiome changes resulting from changing exposures to environmental pollutants and allergens, necessitating new and innovative methods of prevention and treatment. This meeting was especially significant given the world's lack of commitment to addressing critical planetary issues, such as climate change. It is hoped that the meeting theme will at least draw attention once again to the deleterious health effects of climate change.