Exploring Generative Adversarial Networks (GANs) for Synthetic Medical Imaging and Improved Tumor Diagnosis

Medical imaging is a cornerstone of tumor detection and diagnosis, yet challenges such as limited annotated datasets, high acquisition costs, and variability across modalities restrict the accuracy and generalizability of diagnostic models. This study explores the application of “Generative Adversarial Networks (GANs) for synthetic medical imaging to improve tumor diagnosis. Using three benchmark datasets BraTS (brain MRI), LIDC-IDRI (lung CT), and MIAS (mammograms) GAN variants including DCGAN, cGAN, and CycleGAN were employed to generate synthetic tumor images”. The experimental results demonstrate that GAN-generated images achieve high structural fidelity with SSIM values above 0.85 and PSNR exceeding 30 dB, comparable to real scans. When integrated into training pipelines, GAN-augmented datasets improved tumor classification accuracy by 5–6% and segmentation Dice scores by up to 0.08 compared to baseline models. Radiologist evaluations further confirmed the clinical plausibility of synthetic images, indicating their potential to supplement diagnostic training and enhance decision confidence. However, limitations such as mode collapse, image artifacts, and ethical concerns regarding synthetic data usage remain. Overall, the study highlights GANs as a powerful augmentation tool for addressing data scarcity in medical imaging and a promising pathway toward earlier and more reliable tumor diagnosis.

Publication Details

Journal
Journal of Carcinogenesis
Published
2025-09-09
DOI
https://doi.org/10.64149/j.carcinog.24.4s.810-818
Primary Topic
Geochemistry and Geologic Mapping
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Exploring Generative Adversarial Networks (GANs) for Synthetic Medical Imaging and Improved Tumor Diagnosis

Journal of Carcinogenesis
Geochemistry and Geologic Mapping
article

Exploring Generative Adversarial Networks (GANs) for Synthetic Medical Imaging and Improved Tumor Diagnosis

article en

Abstract

Medical imaging is a cornerstone of tumor detection and diagnosis, yet challenges such as limited annotated datasets, high acquisition costs, and variability across modalities restrict the accuracy and generalizability of diagnostic models. This study explores the application of “Generative Adversarial Networks (GANs) for synthetic medical imaging to improve tumor diagnosis. Using three benchmark datasets BraTS (brain MRI), LIDC-IDRI (lung CT), and MIAS (mammograms) GAN variants including DCGAN, cGAN, and CycleGAN were employed to generate synthetic tumor images”. The experimental results demonstrate that GAN-generated images achieve high structural fidelity with SSIM values above 0.85 and PSNR exceeding 30 dB, comparable to real scans. When integrated into training pipelines, GAN-augmented datasets improved tumor classification accuracy by 5–6% and segmentation Dice scores by up to 0.08 compared to baseline models. Radiologist evaluations further confirmed the clinical plausibility of synthetic images, indicating their potential to supplement diagnostic training and enhance decision confidence. However, limitations such as mode collapse, image artifacts, and ethical concerns regarding synthetic data usage remain. Overall, the study highlights GANs as a powerful augmentation tool for addressing data scarcity in medical imaging and a promising pathway toward earlier and more reliable tumor diagnosis.

Journal of CarcinogenesisVol. 24(4s)
Openalex Percentile: Top 37%
Geochemistry and Geologic Mapping
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.