Advances in Formulation Strategies of Floating Microspheres for Gastroretentive Drug Delivery – A Review Article

A key component of gastroretentive drug delivery systems (GRDDS), floating microspheres are intended to increase the bioavailability of medications with limited absorption windows in the upper gastrointestinal tract (GIT) and extend the gastric residence time (GRT). The formulation strategies, mechanisms, evaluation techniques, applications, difficulties, and prospects for the future of floating microspheres are all covered in detail in this thorough review. It highlights the role of cutting-edge technologies, polymer selections, optimisation strategies, and sophisticated preparation techniques in enhancing therapeutic efficacy, all of which are backed by recent research.