Community-acquired Pseudomonas aeruginosa meningitis − A rare case presentation

• Importance of early assessment in patients presenting with fever and confusion. • Prompt appropriate investigations, such as lumbar puncture and cultures to isolate causative organisms. • Initiation of targeted antibiotics (based on sensitivities) with blood–brain barrier permeability in those with meningitis. • Early re-assessment to monitor declining inflammatory markers within 48h of treatment initiation in such cases. • Multi-disciplinary team work to identify and manage uncommon aetiologies such as pseudomonas meningitis. Gram-negative bacterial meningitis has a high mortality rate. We present a case of community acquired bacterial meningitis caused by Pseudomonas aeruginosa with a successful outcome following prolonged intravenous antibiotics. Pseudomonas aeruginosa is an uncommon Gram-negative bacterial cause of meningitis. In its rarity, it has no well-established optimal antibiotic therapy (2) . Patients with the above face a severe clinical picture − of the etiological agents, Gram-negative bacilli have the highest fatality rate; 54%. (3) Therefore, the occurrence of Pseudomonas aeruginosa meningitis in the absence of predisposing factors is both an exceptionally rare, and dangerous, finding (3) – here, we describe such a case.

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Publication Details

Journal
Clinical Infection in Practice
Published
2025-09-12
DOI
https://doi.org/10.1016/j.clinpr.2025.100512
Citations
1
Primary Topic
Geochemistry and Geologic Mapping
Type
article
Field-Weighted Citation Impact
2.48
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article

Community-acquired Pseudomonas aeruginosa meningitis − A rare case presentation

1 citations
Clinical Infection in Practice
Geochemistry and Geologic Mapping
2.48
article

Community-acquired Pseudomonas aeruginosa meningitis − A rare case presentation

article en
1 citations

Abstract

• Importance of early assessment in patients presenting with fever and confusion. • Prompt appropriate investigations, such as lumbar puncture and cultures to isolate causative organisms. • Initiation of targeted antibiotics (based on sensitivities) with blood–brain barrier permeability in those with meningitis. • Early re-assessment to monitor declining inflammatory markers within 48h of treatment initiation in such cases. • Multi-disciplinary team work to identify and manage uncommon aetiologies such as pseudomonas meningitis. Gram-negative bacterial meningitis has a high mortality rate. We present a case of community acquired bacterial meningitis caused by Pseudomonas aeruginosa with a successful outcome following prolonged intravenous antibiotics. Pseudomonas aeruginosa is an uncommon Gram-negative bacterial cause of meningitis. In its rarity, it has no well-established optimal antibiotic therapy (2) . Patients with the above face a severe clinical picture − of the etiological agents, Gram-negative bacilli have the highest fatality rate; 54%. (3) Therefore, the occurrence of Pseudomonas aeruginosa meningitis in the absence of predisposing factors is both an exceptionally rare, and dangerous, finding (3) – here, we describe such a case.

Clinical Infection in PracticeVol. 28
Royal Stoke University Hospital (GB), Keele University (GB)
Good health and well-being
Openalex Percentile: Top 7%
Geochemistry and Geologic Mapping
2.48
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