Mathematical Derivation of Cushing's Triad: Revealing the True Mechanism Through Pressure Change Dynamics.

We present a mathematical derivation showing that Cushing’s triad results from diastolic pressure reduction rather than systolic elevation. Using pressure change dynamics and energy conservation principles within the de Broglie framework for cerebral hemodynamics, we demonstrate that raised intracranial pressure forces opposing changes in arterial pressure components. This explains the consistent clinical observation of systolic pressures around 160-170 mmHg with diastolic pressures of 50-60 mmHg, fundamentally challenging a century of medical teaching.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-09-15
DOI
https://doi.org/10.5281/zenodo.17118299
Primary Topic
Geochemistry and Geologic Mapping
Type
article
Field-Weighted Citation Impact
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article

Mathematical Derivation of Cushing's Triad: Revealing the True Mechanism Through Pressure Change Dynamics.

Zenodo (CERN European Organization for Nuclear Research)
Geochemistry and Geologic Mapping
article

Mathematical Derivation of Cushing's Triad: Revealing the True Mechanism Through Pressure Change Dynamics.

article en

Abstract

We present a mathematical derivation showing that Cushing’s triad results from diastolic pressure reduction rather than systolic elevation. Using pressure change dynamics and energy conservation principles within the de Broglie framework for cerebral hemodynamics, we demonstrate that raised intracranial pressure forces opposing changes in arterial pressure components. This explains the consistent clinical observation of systolic pressures around 160-170 mmHg with diastolic pressures of 50-60 mmHg, fundamentally challenging a century of medical teaching.

Zenodo (CERN European Organization for Nuclear Research)
Openalex Percentile: Top 42%
Geochemistry and Geologic Mapping
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Mathematical Derivation of Cushing's Triad: Revealing the True Mechanism Through Pressure Change Dynamics. · Zenodo (CERN European Organization for Nuclear Research) (2025) | TGRS Research Map | TGRS